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1.
3rd Asia Conference on Computers and Communications, ACCC 2022 ; : 29-34, 2022.
Article in English | Scopus | ID: covidwho-2306230

ABSTRACT

When using the traditional SEIR infectious disease model to predict the trend of novel coronavirus pneumonia epidemic, numerous initial parameters need to be tuned, and the parameters cannot change over time during the prediction process, which reduces the accuracy of the model. Firstly, thesis used a logistic model to preprocess the SEIR model parameters and proposed a SEIR model based on time series recovery rate optimization with a new parameter of effective immunity rate. Secondly, the model was trained with epidemic data from domestic and foreign provinces and cities, and the usability of the model was demonstrated experimentally, and the mean absolute percentage error (MAPE) and goodness of fit (R2) were used to compare with other models, which proved the superiority of the model prediction and indicated further research directions. © 2022 IEEE.

2.
Computer Journal ; 66(4):1030-1039, 2023.
Article in English | Academic Search Complete | ID: covidwho-2302367

ABSTRACT

The Covid-19 pandemic has been identified as a key issue for human society, in recent times. The presence of the infection on any human is identified according to different symptoms like cough, fever, headache, breathless and so on. However, most of the symptoms are shared by various other diseases, which makes it challenging for the medical practitioners to identify the infection. To aid the medical practitioners, there are a number of approaches designed which use different features like blood report, lung and cardiac features to detect the disease. The method captures the lung image using magnetic resonance imaging scan device and records the cardiac features. Using the image, the lung features are extracted and from the cardiac graph, the cardiac features are extracted. Similarly, from the blood samples, the features are extracted. By extracting such features from the person, the method estimates different weight measures to predict the disease. Different methods estimate the similarity of the samples in different ways to classify the input sample. However, the image processing techniques are used for different problems in medical domain;the same has been used in the detection of the disease. Also, the presence of Covid-19 is detected using different set of features by various approaches. [ FROM AUTHOR] Copyright of Computer Journal is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

3.
Lecture Notes in Networks and Systems ; 632:191-205, 2023.
Article in English | Scopus | ID: covidwho-2299963

ABSTRACT

Medical care is vital to having a decent existence. Be that as it may, it is undeniably challenging to get an appointment with a specialist for each medical issue and due to the current global pandemic in the form of Coronavirus, the healthcare industry is under immense pressure to meet the ends of patients' needs. Doctors and nurses are working relentlessly to treat and help the patients in the best possible way and still, they face problems in terms of time management, technical resources, healthcare infrastructure, support staff as well as healthcare personnel. To resolve this problem, we have made a chatbot utilizing Artificial Intelligence (AI) that can analyze the illness and give fundamental insights regarding the infection by looking at the data of a patient who was previously counselled at a health specialist This will also assist in lessening the medical services costs. The chatbot is a product application intended to recreate discussions with human clients through intuitive and customized content. It is in many cases portrayed as the most moving and promising articulations of communication among people and machines utilizing Artificial Intelligence and Natural Language Processing (NLP). The chatbot stores the information in the data set to recognize the sentence and pursue an inquiry choice and answer the corresponding inquiry. Through this paper, we aim to create a fully functional chatbot that will help the patients/users to know about the disease by simply entering the symptoms they possess. Additionally, they can also get information about certain medicine by simply typing the name of the medicine. Another additional feature is the ability of the bot to answer general questions regarding healthcare and wellbeing. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

4.
International Conference on Intelligent Computing and Networking, IC-ICN 2022 ; 632:191-205, 2023.
Article in English | Scopus | ID: covidwho-2271873

ABSTRACT

Medical care is vital to having a decent existence. Be that as it may, it is undeniably challenging to get an appointment with a specialist for each medical issue and due to the current global pandemic in the form of Coronavirus, the healthcare industry is under immense pressure to meet the ends of patients' needs. Doctors and nurses are working relentlessly to treat and help the patients in the best possible way and still, they face problems in terms of time management, technical resources, healthcare infrastructure, support staff as well as healthcare personnel. To resolve this problem, we have made a chatbot utilizing Artificial Intelligence (AI) that can analyze the illness and give fundamental insights regarding the infection by looking at the data of a patient who was previously counselled at a health specialist This will also assist in lessening the medical services costs. The chatbot is a product application intended to recreate discussions with human clients through intuitive and customized content. It is in many cases portrayed as the most moving and promising articulations of communication among people and machines utilizing Artificial Intelligence and Natural Language Processing (NLP). The chatbot stores the information in the data set to recognize the sentence and pursue an inquiry choice and answer the corresponding inquiry. Through this paper, we aim to create a fully functional chatbot that will help the patients/users to know about the disease by simply entering the symptoms they possess. Additionally, they can also get information about certain medicine by simply typing the name of the medicine. Another additional feature is the ability of the bot to answer general questions regarding healthcare and wellbeing. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

5.
J Ambient Intell Humaniz Comput ; : 1-21, 2021 Sep 18.
Article in English | MEDLINE | ID: covidwho-2261136

ABSTRACT

Since the arrival of the novel Covid-19, several types of researches have been initiated for its accurate prediction across the world. The earlier lung disease pneumonia is closely related to Covid-19, as several patients died due to high chest congestion (pneumonic condition). It is challenging to differentiate Covid-19 and pneumonia lung diseases for medical experts. The chest X-ray imaging is the most reliable method for lung disease prediction. In this paper, we propose a novel framework for the lung disease predictions like pneumonia and Covid-19 from the chest X-ray images of patients. The framework consists of dataset acquisition, image quality enhancement, adaptive and accurate region of interest (ROI) estimation, features extraction, and disease anticipation. In dataset acquisition, we have used two publically available chest X-ray image datasets. As the image quality degraded while taking X-ray, we have applied the image quality enhancement using median filtering followed by histogram equalization. For accurate ROI extraction of chest regions, we have designed a modified region growing technique that consists of dynamic region selection based on pixel intensity values and morphological operations. For accurate detection of diseases, robust set of features plays a vital role. We have extracted visual, shape, texture, and intensity features from each ROI image followed by normalization. For normalization, we formulated a robust technique to enhance the detection and classification results. Soft computing methods such as artificial neural network (ANN), support vector machine (SVM), K-nearest neighbour (KNN), ensemble classifier, and deep learning classifier are used for classification. For accurate detection of lung disease, deep learning architecture has been proposed using recurrent neural network (RNN) with long short-term memory (LSTM). Experimental results show the robustness and efficiency of the proposed model in comparison to the existing state-of-the-art methods.

6.
Comput Methods Biomech Biomed Engin ; : 1-19, 2023 Apr 05.
Article in English | MEDLINE | ID: covidwho-2264842

ABSTRACT

The COVID-19 virus has affected many people around the globe with several issues. Moreover, it causes a worldwide pandemic, and it makes more than one million deaths. Countries around the globe had to announce a complete lockdown when the corona virus causes the community to spread. In real-time, Polymerase Chain Reaction (RT-PCR) test is conducted to detect COVID-19, which is not effective and sensitive. Hence, this research presents the proposed Caviar-MFFO-assisted Deep LSTM scheme for COVID-19 detection. In this research, the COVID-19 cases data is utilized to process the COVID-19 detection. This method extracts the various technical indicators that improve the efficiency of COVID-19 detection. Moreover, the significant features fit for COVID-19 detection are selected using proposed mayfly with fruit fly optimization (MFFO). In addition, COVID-19 is detected by Deep Long Short Term Memory (Deep LSTM), and the Conditional Autoregressive Value at Risk MFFO (Caviar-MFFO) is modeled to train the weight of Deep LSTM. The experimental analysis reveals that the proposed Caviar-MFFO assisted Deep LSTM method provided efficient performance based on the Mean Squared Error (MSE) and Root Mean Squared Error (RMSE), and achieved the recovered cases with the minimal values of 1.438 and 1.199, whereas the developed model achieved the death cases with the values of 4.582 and 2.140 for MSE and RMSE. In addition, 6.127 and 2.475 are achieved by the developed model based on infected cases.

7.
Comput Electr Eng ; 108: 108675, 2023 May.
Article in English | MEDLINE | ID: covidwho-2281378

ABSTRACT

COVID-19 disrupted lives and livelihoods and affected various sectors of the economy. One such domain was the already overburdened healthcare sector, which faced fresh challenges as the number of patients rose exponentially and became difficult to deal with. In such a scenario, telemedicine, teleconsultation, and virtual consultation became increasingly common to comply with social distancing norms. To overcome this pressing need of increasing 'remote' consultations in the 'post-COVID' era, the Internet of Things (IoT) has the potential to play a pivotal role, and this present paper attempts to develop a novel system that implements the most efficient machine learning (ML) algorithm and takes input from the patients such as symptoms, audio recordings, available medical reports, and other histories of illnesses to accurately and holistically predict the disease that the patients are suffering from. A few of the symptoms, such as fever and low blood oxygen, can also be measured via sensors using Arduino and ESP8266. It then provides for the appropriate diagnosis and treatment of the disease based on its constantly updated database, which can be developed as an application-based or website-based platform.

8.
Comput Methods Biomech Biomed Engin ; : 1-23, 2022 Oct 11.
Article in English | MEDLINE | ID: covidwho-2249671

ABSTRACT

Multi-disease prediction is regarded as the capacity to simultaneously identify various diseases that are expected to be affected an individual at a certain period. These multiple diseases are seemed to be at various progression levels and need to be detected in the patient at the time of clinical visits. Diverse studies in the literature have included the predictive models for particular diseases yet, it is unable to notice humans with multiple diseases since humans are mostly suffered not only from a single disease but also from multiple diseases. Hence, this article aims to implement a novel multi-disease prediction model using an ensemble learning approach with deep features. The required data for the multi-disease prediction is collected from the standard datasets. Then, the collected data are given into the "Deep Belief Network (DBN)" approach, where the features are obtained from the RBM layers. These RBM features are tuned with the help of Deviation-based Hybrid Grasshopper Barnacles Mating Optimization (D-HGBMO) for improving the prediction performance. The optimized RBM features are considered in the ensemble learning model named Ensemble, in which the multi-disease prediction is performed with "Deep Neural Network (DNN), Extreme Learning Machine (ELM), and Long Short Term Memory." The predicted score from three classifiers is used in the optimized weighted score and thresholding-based final prediction using the same D-HGBMO for determining the accurate multi-disease prediction results. The experimental results show the effective performance of the proposed model by comparing it with the existing classifiers with the help of different quantitative measures.

9.
Comput Electr Eng ; 102: 108224, 2022 Sep.
Article in English | MEDLINE | ID: covidwho-2247861

ABSTRACT

Due to the COVID-19 epidemic and the curfew caused by it, many people have sought to find an ADPS on the internet in the last few years. This hints to a new age of medical treatment, all the more so if the number of internet users continues to expand. As a result, automatic illness prediction online applications have attracted the interest of a large number of researchers worldwide. This work aims to develop and implement an automated illness prediction system based on speech. The system will be designed to forecast the sort of ailment a patient is suffering from based on his voice, but this was not feasible during the trial, therefore the diseases were divided into three categories (painful, light pain and psychological pain), and then the diagnose process were implemented accordingly. The medical dataset named "speech, transcription, and intent" served as the baseline for this study. The smoothness, MFCC, and SCV properties were used in this work, which demonstrated their high representation to human being medical situations. The noise reduction forward-backward filter was used to eliminate noise from wave files captured online in order to account for the high level of noise seen in the deployed dataset. For this study, a hybrid feature selection method was created and built that combined the output of a genetic algorithm (GA) with the inputs of a NN algorithm. Classification was performed using SVM, neural network, and GMM. The greatest results obtained were 94.55% illness classification accuracy in terms of SVM. The results showed that diagnosing illness through speech is a difficult process, especially when diagnosing each type of illness separately, but when grouping the different illness types into groups, depending on the amount of pain and the psychological situation of the patient, the results were much higher.

10.
International Journal of Electronic Healthcare ; 13(1):71-90, 2023.
Article in English | Scopus | ID: covidwho-2242384

ABSTRACT

Healthcare is one of the flourishing sectors in each developed and emerging economy. Due to this vast COVID-19 pandemic, the traditional healthcare system cannot provide adequate facilities due to a lack of interactions between doctors and patients. In such conditions, e-healthcare is contributing towards the accelerating growth within the healthcare industry by providing the latest information technology to support information search and communication processes. Besides this, a machine learning algorithm is used to intensify the smartness of the healthcare industry. The five major components of an e-healthcare system are cost-saving, virtual networking, electronic medical record physician-patient relationships and privacy concerns. Our proposed system provides location-based e-prescribing, e-reports, disease prediction, and suggesting treatments and emergency services with a single click, so it is better than another existing system. Copyright © 2023 Inderscience Enterprises Ltd.

11.
Biomedical Signal Processing and Control ; 82, 2023.
Article in English | Scopus | ID: covidwho-2241802

ABSTRACT

Prioritizing candidate genes is essential for genome-based diagnostics of various hereditary disorders. Furthermore, it is a difficult task with particular and noisy information about genes, illnesses, and relationships. Although several computer methods for disease gene prioritization have been developed, their efficiency is limited by manually created traits, network architecture, or pre-established data fusion criteria. Hence, this research proposes a unique gene prioritization and disease prediction model. Initially, the gathered information is pre-processed by a data cleaning model. In the proposed gene prioritization phase, the pre-processed data are tokenized. Then a new knowledge-based ontology structure is constructed with the improved skewness-based semantic similarity function. The ensemble classifier is constructed along Recurrent Neural Network (RNN), optimized fuzzy logic, and also Deep Belief Network (DBN) to forecast the gene disorders in the prediction phase. The retrieved features from the feature extraction phase are used to train RNN;while the extracted knowledge bases are used to train the DBN, then the results are fed into the optimized fuzzy logic. The fuzzy logic is the primary indication;its fuzzification function is fine-tuned employing a methodology to improve illness prediction accuracy. A recommended new hybrid system, named as Cauchy's Mutated Corona Virus Optimization Algorithm (CMCOA), is the upgraded version of the CVOA, a typical coronavirus optimization technique. Finally, to evaluate the efficiency of the projected model, a comparison of the suggested and existent models is performed with respect to various measures. In particular, the proposed model has recorded the highest accuracy as 93 % at 60 % of training, which is 42.5 %, 36.1 %, 33.3 %, 41.1 %, 48.5 %, 48.5 %, 9 %, 8 %, 8 %, 8 %, 8 %, and 14.5 % improved over existing models like GCN, GCN [6], SVM, CNN, Bi-LSTM, LSTM, GRU, fuzzy, EC + GOA, EC + SSO, EC + CMBO, EC + SMA and EC + CCVOA, respectively. The precision of the suggested work with improved features &CMCOA is 15.5 %, and 14.42 % superior to the proposed work without existing features & CMCOA and proposed work with existing features & CMCOA approaches. © 2022 Elsevier Ltd

12.
Lecture Notes in Networks and Systems ; 401:41-48, 2023.
Article in English | Scopus | ID: covidwho-2238786

ABSTRACT

Since 2020, the world has been impacted badly by the pandemic situation that arose due to the coronavirus. Artificial intelligence plays a crucial role in the healthcare system, specifically identifying symptoms of disease with the help of various machine learning algorithms during the diagnosis stage. The identified symptoms in various diagnostic tests are used to predict the clinical outcome of early detection of diseases, which results in human life saving. Machine learning algorithms have been successfully used in automated interpretation. With the advanced technology of cybersecurity aspects, we can emphasize data protection for better results. Artificial intelligence can enhance the security of medical science data. Furthermore, they improvise cybersecurity techniques with machine learning technologies. © 2023, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

13.
Baltic Journal of Modern Computing ; 10(4):574-610, 2022.
Article in English | Scopus | ID: covidwho-2205108

ABSTRACT

The outcome of human viral infections is highly dependent on the host features. The scale of COVID-19 spread and amount of deaths caused motivate scientists to search for ways to combat this pandemic. We have reviewed 34 scientific papers taking into account two main points of COVID-19: the biology behind the infection and the methods used to model the outcome of the disease. The findings of the studies suggest that host genetic factors impact the clinical manifestation and outcome of COVID-19. Scientists are modelling COVID-19 using various computational methods, including genome-wide, exome-wide, and phenome-wide association analyses. Machine learning and some other methods are used to model COVID-19 to obtain new insights into the pathogenesis of the disease. As for now, there is a limited number of causal studies about COVID-19 and host genetic factors. © 2022 University of Bologna. All rights reserved.

14.
3rd International Conference on Smart Electronics and Communication, ICOSEC 2022 ; : 1301-1307, 2022.
Article in English | Scopus | ID: covidwho-2191914

ABSTRACT

COVID-19 is a virus-borne malady. A clinical study of infected COVID-19 patients found that most COVID-19 patients suffered lung infection after contracting the disease. Consequently, chest X-rays are a more effective and lower-cost imaging technique for diagnosing lung-related problems. This study used deep learning models, including MobileNetV2,DenseNet201, ResNet50, and VGG19, for COVID-19 prediction. For the study, we used chest X-ray image data for binary classification of COVID-19. 7207 chest X-ray image data were obtained from the Kaggle repository, with 5761 being utilized for training and 1446 being used for validation. A comparative analysis was conducted among the models and examined their accuracy. It has been determined that the DenseNet201 models achieved the highest accuracy of 93.02% for detecting COVID-19 in the lowest compilation time of 27secs. The models, MobileNetV2, ResNet50, and VGG19 had the accuracy rate of 77.28%, 65.86% and 74.92%, respectively. The research indicates that the DenseNet201 model is the most effective in detecting COVID-19 using x-ray imaging. © 2022 IEEE.

15.
Biomedical Signal Processing and Control ; 82:104548, 2023.
Article in English | ScienceDirect | ID: covidwho-2176931

ABSTRACT

Prioritizing candidate genes is essential for genome-based diagnostics of various hereditary disorders. Furthermore, it is a difficult task with particular and noisy information about genes, illnesses, and relationships. Although several computer methods for disease gene prioritization have been developed, their efficiency is limited by manually created traits, network architecture, or pre-established data fusion criteria. Hence, this research proposes a unique gene prioritization and disease prediction model. Initially, the gathered information is pre-processed by a data cleaning model. In the proposed gene prioritization phase, the pre-processed data are tokenized. Then a new knowledge-based ontology structure is constructed with the improved skewness-based semantic similarity function. The ensemble classifier is constructed along Recurrent Neural Network (RNN), optimized fuzzy logic, and also Deep Belief Network (DBN) to forecast the gene disorders in the prediction phase. The retrieved features from the feature extraction phase are used to train RNN;while the extracted knowledge bases are used to train the DBN, then the results are fed into the optimized fuzzy logic. The fuzzy logic is the primary indication;its fuzzification function is fine-tuned employing a methodology to improve illness prediction accuracy. A recommended new hybrid system, named as Cauchy's Mutated Corona Virus Optimization Algorithm (CMCOA), is the upgraded version of the CVOA, a typical coronavirus optimization technique. Finally, to evaluate the efficiency of the projected model, a comparison of the suggested and existent models is performed with respect to various measures. In particular, the proposed model has recorded the highest accuracy as 93 % at 60 % of training, which is 42.5 %, 36.1 %, 33.3 %, 41.1 %, 48.5 %, 48.5 %, 9 %, 8 %, 8 %, 8 %, 8 %, and 14.5 % improved over existing models like GCN, GCN [6], SVM, CNN, Bi-LSTM, LSTM, GRU, fuzzy, EC + GOA, EC + SSO, EC + CMBO, EC + SMA and EC + CCVOA, respectively. The precision of the suggested work with improved features &CMCOA is 15.5 %, and 14.42 % superior to the proposed work without existing features & CMCOA and proposed work with existing features & CMCOA approaches.

16.
The Computer Journal ; 2022.
Article in English | Web of Science | ID: covidwho-2151958

ABSTRACT

The Covid-19 pandemic has been identified as a key issue for human society, in recent times. The presence of the infection on any human is identified according to different symptoms like cough, fever, headache, breathless and so on. However, most of the symptoms are shared by various other diseases, which makes it challenging for the medical practitioners to identify the infection. To aid the medical practitioners, there are a number of approaches designed which use different features like blood report, lung and cardiac features to detect the disease. The method captures the lung image using magnetic resonance imaging scan device and records the cardiac features. Using the image, the lung features are extracted and from the cardiac graph, the cardiac features are extracted. Similarly, from the blood samples, the features are extracted. By extracting such features from the person, the method estimates different weight measures to predict the disease. Different methods estimate the similarity of the samples in different ways to classify the input sample. However, the image processing techniques are used for different problems in medical domain;the same has been used in the detection of the disease. Also, the presence of Covid-19 is detected using different set of features by various approaches.

17.
2022 International Conference on Innovative Computing, Intelligent Communication and Smart Electrical Systems, ICSES 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2136319

ABSTRACT

Corona Virus or Covid-19 Disease, a term which creates a mass affection to all the countries in both Human life as well as economy wise. This disease causes a huge destruction in many person's individual life and most of the people around the world died due to this cause. Several assessments and researches are going on to predict the disease in fine manner as well as identify the disease over earlier stages to save the life of people without any delay. However, the most prominent and acceptable way of predicting the Corona Virus is by using the Lung Computed Tomography (CT) images. The Lung based CT images provides a huge support to identify the Covid virus on earlier stages, in which the people are advised to take such type of scanning while infected with corona virus. An earlier stage identification of Corona Virus is the basic need now-a-days, in which the disease is identified initially, means it can easily be cured. The identification of Covidvirus over lung CT images is of course a complex task because the CT images contains low-intensity pixels and the contrast level variations are different on various images. So it is complex to manipulate such images in practical, due to this a novel Digital Image Processing scheme is required to provide an efficient support to the respective physician to identify the Corona Virus on earlier stages in clear manner. The concept of machine learning is adopted over this paper to provide a proper predictions as well as the logic of dual classification algorithms are combined together to form a new machine learning strategy to attain high accuracy with enhanced prediction probabilities. The logic of Deep Neural Network (DNN) is modulated with respect to the logic of Random Forest (RF) Classification algorithm to make a new methodology called Hybrid Learning based Disease Prediction Scheme (HLDPS). In which this proposed approach associates the benefits of both DNN and RF into this prediction strategy to make an appropriate predictions over lung CT images and report the level of severity based on the cell vector distance. The resulting section of this paper provides proper experimental proof of the mentioned things in clear manner with graphical representations. For all the proposed approach of HLDPS is sufficient to predict the Corona Virus on earlier stages based on lung CT images in fine manner and the associated proofs are specified clearly on resulting section of this paper. © 2022 IEEE.

18.
Microbiome ; 10(1): 121, 2022 08 05.
Article in English | MEDLINE | ID: covidwho-2139419

ABSTRACT

BACKGROUND: With the rapid accumulation of microbiome-wide association studies, a great amount of microbiome data are available to study the microbiome's role in human disease and advance the microbiome's potential use for disease prediction. However, the unique features of microbiome data hinder its utility for disease prediction. METHODS: Motivated from the polygenic risk score framework, we propose a microbial risk score (MRS) framework to aggregate the complicated microbial profile into a summarized risk score that can be used to measure and predict disease susceptibility. Specifically, the MRS algorithm involves two steps: (1) identifying a sub-community consisting of the signature microbial taxa associated with disease and (2) integrating the identified microbial taxa into a continuous score. The first step is carried out using the existing sophisticated microbial association tests and pruning and thresholding method in the discovery samples. The second step constructs a community-based MRS by calculating alpha diversity on the identified sub-community in the validation samples. Moreover, we propose a multi-omics data integration method by jointly modeling the proposed MRS and other risk scores constructed from other omics data in disease prediction. RESULTS: Through three comprehensive real-data analyses using the NYU Langone Health COVID-19 cohort, the gut microbiome health index (GMHI) multi-study cohort, and a large type 1 diabetes cohort separately, we exhibit and evaluate the utility of the proposed MRS framework for disease prediction and multi-omics data integration. In addition, the disease-specific MRSs for colorectal adenoma, colorectal cancer, Crohn's disease, and rheumatoid arthritis based on the relative abundances of 5, 6, 12, and 6 microbial taxa, respectively, are created and validated using the GMHI multi-study cohort. Especially, Crohn's disease MRS achieves AUCs of 0.88 (0.85-0.91) and 0.86 (0.78-0.95) in the discovery and validation cohorts, respectively. CONCLUSIONS: The proposed MRS framework sheds light on the utility of the microbiome data for disease prediction and multi-omics integration and provides a great potential in understanding the microbiome's role in disease diagnosis and prognosis. Video Abstract.


Subject(s)
COVID-19 , Crohn Disease , Microbiota , Disease Susceptibility , Humans , Microbiota/genetics , Risk Factors
19.
One Health ; 15: 100439, 2022 Dec.
Article in English | MEDLINE | ID: covidwho-2061735

ABSTRACT

The complex, unpredictable nature of pathogen occurrence has required substantial efforts to accurately predict infectious diseases (IDs). With rising popularity of Machine Learning (ML) and Deep Learning (DL) techniques combined with their unique ability to uncover connections between large amounts of diverse data, we conducted a PRISMA systematic review to investigate advances in ID prediction for human and animal diseases using ML and DL. This review included the type of IDs modeled, ML and DL techniques utilized, geographical distribution, prediction tasks performed, input features utilized, spatial and temporal scales, error metrics used, computational efficiency, uncertainty quantification, and missing data handling methods. Among 237 relevant articles published between January 2001 and May 2021, highly contagious diseases in humans were most often represented, including COVID-19 (37.1%), influenza/influenza-like illnesses (9.3%), dengue (8.9%), and malaria (5.1%). Out of 37 diseases identified, 51.4% were zoonotic, 37.8% were human-only, and 8.1% were animal-only, with only 1.6% economically significant, non-zoonotic livestock diseases. Despite the number of zoonoses, 86.5% of articles modeled humans whereas only a few articles (5.1%) contained more than one host species. Eastern Asia (32.5%), North America (17.7%), and Southern Asia (13.1%) were the most represented locations. Frequent approaches included tree-based ML (38.4%) and feed-forward neural networks (26.6%). Articles predicted temporal incidence (66.7%), disease risk (38.0%), and/or spatial movement (31.2%). Less than 10% of studies addressed uncertainty quantification, computational efficiency, and missing data, which are essential to operational use and deployment. This study highlights trends and gaps in ML and DL for ID prediction, providing guidelines for future works to better support biopreparedness and response. To fully utilize ML and DL for improved ID forecasting, models should include the full disease ecology in a One-Health context, important food and agricultural diseases, underrepresented hotspots, and important metrics required for operational deployment.

20.
Advances in Science, Technology and Innovation ; : 187-202, 2022.
Article in English | Scopus | ID: covidwho-2048081

ABSTRACT

The Internet-of-Things (IoT) is modifying the infrastructure of technologies through interactions among various modules and components. It has enabled the setting up of complex systems such as smart homes, smart traffic control systems and smart environments. After COVID-19 pandemic, it is becoming more and more difficult to maintain a healthy and secure environment on university grounds. This chapter presents an IoT-based smart health system implemented on a university campus. The smart health system allows people on campus to closely keep track of their health status. A web application has been developed to provide real-time information of their vitals through medical sensors connected to a microcontroller (Arduino) for data acquisition. For disease prediction, a disease prediction module uses the sensor data and a health form to predict three main diseases: cold flu, hypertension and diabetes. To perform prediction, three models namely the cold flu model, hypertension model and diabetes model have been trained on different machine learning algorithms where the most accurate models are deployed in the web application. The cold flu model is evaluated using five different non-linear classification algorithms namely, decision tree (99%), random forest (99.5%), naïve bayes (94.9%), K-Nearest-Neighbour (89.7%) and SVM (55.3%) while hypertension model having a linear distribution is evaluated using three linear classification algorithms namely, logistic regression (86.0%), linear SVM (99.3%) and stochastic gradient descent (49.6%). Besides, the diabetes model is evaluated using logistic regression (88.7%), linear SVM (93.3%), decision tree (98.0%) and KNN (93.3%). The user is alerted of his diagnosis by email. Moreover, the IoT- based smart health system consists of features such as online booking of appointments, health history and a medication section. Proper treatment can therefore be administered based on the users’ health details, diagnosis and medication, if any. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

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